What Factors Are Driving the Surge in Global Rheumatoid Arthritis Since 1980?

Synopsis
Key Takeaways
- Increase in Elderly Population: Contributing to the rising burden of rheumatoid arthritis.
- Smoking Prevalence: A crucial factor affecting disease incidence.
- Sociodemographic Disparities: Highlighting inequalities in healthcare access and outcomes.
- Global Trends: Continuous rise in prevalence, especially among younger populations.
- Future Predictions: Potential increases in disability-adjusted life years in low-middle SDI regions by 2040.
New Delhi, June 16 (NationPress) The rise in the elderly demographic and the increasing prevalence of smoking are the key factors contributing to the escalating global burden of rheumatoid arthritis since 1980, as revealed by a study utilizing AI technology.
Rheumatoid arthritis is a persistent autoimmune disorder that mainly impacts the joints, leading to pain, swelling, and stiffness.
The groundbreaking study published in the Annals of the Rheumatic Diseases highlights considerable socioeconomic disparities and the growing inequalities associated with disease burden.
The research findings indicate that demographic ageing, population expansion, and uneven healthcare resources worsen the impact of rheumatoid arthritis in various regions.
By analyzing data from the Global Burden of Disease (GBD), the study employed an innovative deep learning framework, incorporating the largest spatiotemporal dataset of rheumatoid arthritis from 1980 to 2021 across 953 locations worldwide.
The analysis demonstrated a continuous rise in the global burden of rheumatoid arthritis from 1980 to 2021, with a pronounced increase among younger demographics and across diverse geographic areas.
Importantly, the inequality in disability-adjusted life years (DALYs) surged by 62.55 percent since 1990, with Finland, Ireland, and New Zealand identified as the most unequal nations in 2021.
Economic factors were not the only influences on the burden of rheumatoid arthritis.
Regions with a high sociodemographic index (SDI) like Japan and the UK displayed differing trends in disease burden.
Japan’s declining DALY rates, despite a high SDI, may be attributed to effective national early diagnosis initiatives, extensive utilization of biologic therapies, and a diet rich in anti-inflammatory elements.
“By 2040, regions with low to middle SDI may experience rising DALYs due to population ageing and growth, while high SDI areas could see a decline,” stated the researchers led by Queran Lin, principal investigator at Imperial College London.
“Reducing smoking could potentially lower rheumatoid arthritis mortality by 16.8 percent and DALYs by 20.6 percent in high-smoking countries like China, providing significant advantages for both medium and high SDI regions,” the team added.
The researchers emphasized that numerous regions worldwide still lack the essential evidence base to guide precision health policies and targeted interventions.