Can Exercise Counteract Depression Symptoms Induced by Junk Food Diet?

Synopsis
Key Takeaways
- Exercise can counteract junk food's mental health effects.
- Running showed antidepressant-like benefits.
- Diet alters gut metabolites affecting mood.
- Physical activity improves brain function even on poor diets.
- Combining exercise with good nutrition maximizes mental health benefits.
New Delhi, Oct 21 (NationPress) Individuals consuming a higher amount of junk food can alleviate its detrimental effects on mental well-being through cardio workouts such as running, as revealed by an animal study released on Tuesday.
Researchers from University College Cork in Ireland pinpointed specific metabolic pathways that illustrate how exercise counteracts the adverse behavioral impacts of a Western-style diet.
The study indicated that voluntary running can alleviate depression-like behaviors triggered by high-fat and high-sugar diets, influencing both circulating hormones and gut-derived metabolites.
“These findings offer essential insights into how lifestyle changes can be tailored to enhance mental health in today's world of prevalent ultra-processed food consumption,” stated Professor Yvonne Nolan from the university.
Published in the peer-reviewed journal Brain Medicine, the research involved adult male rats exposed to either standard food or a varied cafeteria diet rich in high-fat and high-sugar options over a span of seven and a half weeks, with half of each group having access to running wheels.
The results demonstrated that voluntary wheel running had an antidepressant-like effect even in subjects with poor dietary quality, suggesting that physical activity can benefit those on Western-style diets.
Professor Nolan and her team discovered that the diet significantly altered the gut metabolome, affecting 100 out of 175 metabolites measured in inactive animals.
“Exercise exhibited more selective effects, adjusting only a subset of these alterations. Three metabolites closely associated with mood regulation—anserine, indole-3-carboxylate, and deoxyinosine—were reduced by the cafeteria diet but partially restored through exercise,” Nolan noted.
Moreover, the research employed comprehensive behavioral assessments to evaluate various aspects of brain functionality.
While junk food consumption did not notably impair spatial learning or recognition memory in the rats, exercise led to slight enhancements in spatial navigation.
The research team also investigated anxiety-like behaviors, observing subtle anxiolytic effects from exercise, irrespective of the diet consumed.
These findings imply that while exercise can enhance mood regardless of dietary quality, achieving complete neuroplastic benefits may necessitate attention to nutritional health. This holds significance for crafting interventions that maximize both practicality and biological impact, the researchers concluded.