Could Tiny Metal Particles Revolutionize Cancer Treatment?
Synopsis
Key Takeaways
- Microscopic metal particles can target cancer cells.
- They spare healthy tissue, reducing toxicity.
- Research is led by the Royal Melbourne Institute of Technology.
- Particles named nanodots release reactive oxygen.
- They show promise in treating cervical cancer.
New Delhi, Oct 24 (NationPress) A group of researchers has created microscopic metal particles capable of destroying cancer cells while preserving healthy tissue, paving the way for potentially more precise and less harmful cancer therapies.
This research by a team at the Royal Melbourne Institute of Technology (RMIT) in Australia is currently in the cell-culture phase and has yet to be evaluated in animal or human trials, as reported by Xinhua news agency.
Nevertheless, it introduces a novel approach to developing cancer treatments by leveraging the inherent vulnerabilities of cancer.
The international team, led by RMIT researchers, engineered minuscule particles called nanodots from molybdenum oxide, a compound derived from the rare metal molybdenum, which is commonly utilized in electronics and alloys.
By modifying their chemical makeup, the scientists allowed the particles to discharge reactive oxygen molecules—unstable forms of oxygen that inflict damage on cancer cells and induce their self-destruction.
In laboratory tests, these particles eliminated three times more cervical cancer cells compared to healthy cells within 24 hours, all without requiring light, which is atypical for techniques that depend on oxidative stress, according to the study published in the journal Advanced Science.
“Cancer cells inherently exist under more stress than healthy cells. Our particles exacerbate that stress just enough to provoke self-destruction in cancer cells, while healthy cells manage adequately,” stated Zhang Baoyue, the lead author from the RMIT School of Engineering.
“The outcome was particles that selectively induce oxidative stress in cancer cells in laboratory settings,” Zhang explained.
Most cancer therapies impact both malignant and healthy tissues; however, technologies that specifically stress cancer cells may lead to gentler, more targeted treatment options, the researchers noted.
They further mentioned that these particles are crafted from a common metal oxide rather than expensive or hazardous noble metals such as gold or silver, making them more likely to be affordable and safer to produce.