IIT Gandhinagar Unveils Hydrogel Technology Revolutionizing Colon Tumor Surgery
Synopsis
Key Takeaways
Gandhinagar, April 19 (NationPress) In a significant breakthrough, researchers at IIT Gandhinagar have introduced a novel hydrogel-based technology designed to enhance the surgical process for colon tumors.
This innovative technology utilizes biocompatible polymers to enable local, controlled, and intelligent drug delivery, which not only increases treatment effectiveness but also reduces systemic toxicity.
Harshil Dave, a talented scientist from Mehsana, has played a pivotal role in this advancement in medical science, explaining how this technology represents a substantial improvement in the management of colon tumors.
The hydrogel technology is particularly beneficial for the surgical excision of colorectal polyps, which are precursors to cancer.
According to Harshil, the hydrogel he developed exhibits a remarkable shear-thinning characteristic.
This property allows the substance to transition into a liquid state under pressure, and then revert to its solid form once the pressure is alleviated.
This unique feature enables physicians to inject the hydrogel through a long catheter or endoscope. Once injected, it forms a supportive cushion beneath the tumor, assisting surgeons in lifting and removing the tissue with enhanced accuracy.
Traditionally, saline or dextrose is injected under a colon tumor during endoscopic procedures to elevate it, but these fluids are often rapidly absorbed.
In contrast, the new hydrogel maintains the tumor's elevation and stability, significantly facilitating the surgical operation.
Mukesh Danka, an Assistant Professor in the Department of Biological Sciences and Engineering at IIT Gandhinagar, endorsed Harshil's findings, stating, "Harshil began his research three years ago. We sourced DGMS molecules from plants. Upon dissolving these in water, we discovered they formed a nanofibrous hydrogel. Harshil then proceeded to develop this material further."
He emphasized that small cancerous tumors frequently arise within our gastrointestinal tract.
Harshil Dave's groundbreaking research has been published in a prestigious international journal, and he has received the 'Vikram Sarabhai Young Scientist Award 2026' for his contributions.
Currently, this technology has successfully completed pre-clinical trials on large animals.
Plans are underway to advance it to clinical trials, aiming for widespread use in colon cancer treatment in the near future.