Can Gut Bacteria Aid Weight Loss and Improve Metabolic Health?
Synopsis
Key Takeaways
- Turicibacter may support weight loss.
- Research conducted on mice shows promising results.
- Link between gut bacteria and metabolic health was established.
- High ceramide levels are associated with metabolic disorders.
- Future studies may focus on human applications.
New Delhi, Dec 20 (NationPress) Researchers in the United States have discovered a gut bacterium that may facilitate weight loss and enhance metabolic health.
This finding emerges amidst various weight-loss injections and medications that have demonstrated effectiveness in helping individuals shed pounds.
In experiments conducted on mice, the research team from the University of Utah identified a distinct type of gut bacterium known as Turicibacter, which has the potential to enhance metabolic health and mitigate weight gain.
Individuals suffering from obesity typically possess lower levels of Turicibacter, implying that this microbe could also support healthy weight maintenance in humans. The findings could pave the way for innovative methods to manage weight by modifying gut bacteria, as noted by the researchers in their publication in Cell Metabolism.
Turicibacter, which appears rod-shaped, was shown to independently lower blood sugar, reduce fat levels in the bloodstream, and decrease weight gain in mice subjected to a high-fat diet.
However, the benefits of Turicibacter are likely not exclusive; numerous gut bacteria may play a role in metabolic health. Moreover, results derived from animal models may not necessarily translate to humans.
“While we have seen reduced weight gain in mice, I cannot confirm if this translates to humans,” stated Round.
Nonetheless, the researchers remain optimistic that Turicibacter could serve as a foundation for developing therapies aimed at promoting healthy metabolism and preventing excessive weight gain.
The research indicates that Turicibacter may enhance metabolic health by influencing the host's production of a fatty molecule known as ceramides.
Ceramide levels spike with high-fat diets, and elevated ceramide levels are linked to various metabolic disorders, including type 2 diabetes and heart disease. Remarkably, the fats produced by Turicibacter can maintain low ceramide levels, even among mice consuming a high-fat diet.
“Through further exploration of specific microbes, we could potentially convert microbes into medicinal treatments and identify bacteria that can create a consortium of different strains for individuals suffering from various diseases,” remarked Kendra Klag, the study's lead author.