How Does Maternal Exposure to Pollution Affect Fetal Brain Structures?

Synopsis
A recent study reveals concerning links between maternal exposure to pollution and changes in fetal brain structures. Highlighting the vulnerability of the developing brain during critical growth periods, the findings raise awareness about the potential long-term impacts of environmental factors on unborn children.
Key Takeaways
- Maternal exposure to pollution can alter fetal brain structures.
- Critical development phases are particularly vulnerable.
- Pollutants like NO₂ and PM2.5 have significant effects.
- Increased awareness and education are essential.
- Further research is needed to validate findings.
New Delhi, June 13 (NationPress) Maternal exposure to pollution, especially during the second and third trimesters of pregnancy, has been found to influence specific brain structures of developing fetuses, according to a recent study.
The research, published in The Lancet Planetary Health, indicates that these alterations are associated with brain imbalances, diminished motor coordination, and delayed growth.
"During mid to late gestation, the fetal brain undergoes a crucial developmental phase, rendering it particularly susceptible to external influences such as pollution," stated Payam Dadvand, a researcher at the Barcelona Institute for Global Health (ISGlobal) in Spain.
Elisa Llurba and Lola Gómez-Roig, clinicians at the Hospital de Sant Pau and BCNatal-Hospital Sant Joan de Déu, respectively, added, "As healthcare professionals, we are observing compelling evidence indicating that even in pregnancies that seem healthy by all conventional criteria, factors like air pollution can subtly impact fetal brain development."
The researchers examined data gathered from 2018 to 2021 involving 754 mother-fetus pairs.
A specialized ultrasound technique known as transvaginal neurosonography during the third trimester revealed that prenatal exposure to nitrogen dioxide (NO₂), particulate matter (PM2.5), and black carbon resulted in an increase in the volume of various brain cavities that contain cerebrospinal fluid.
Particularly, direct correlations were found between exposure to these pollutants and an increased volume of the lateral ventricles, which are located in each hemisphere of the brain, as well as an enlargement of the cisterna magna, a cavity situated in the lower part of the brain.
Additionally, an increase in the width of the cerebellar vermis—the central area of the cerebellum, crucial for balance and motor coordination—was also noted.
The findings also indicate less maturation of the brain.
"The key takeaway is that these differences, while small on an individual level, are indeed significant from a population perspective, as they shed light on how pollution impacts the fetal brain and its sensitivity to environmental exposures," commented Laura Gómez-Herrera, a researcher at ISGlobal.
The researchers underscored the necessity for additional studies to validate these findings and emphasized the importance of heightened awareness and education within both the health community and society at large.