Can Your Morning Cup of Coffee Really Slow Down Aging and Boost Longevity?

Synopsis
Key Takeaways
- Caffeine may slow down aging by activating AMPK.
- It can enhance cellular energy management.
- The study opens new pathways for health research and interventions.
- AMPK is also targeted by medications like metformin.
- Future studies may reveal more about caffeine's benefits.
New Delhi, June 28 (NationPress) Do you cherish your morning cup of coffee? A recent study indicates that it may not just energize you, but also play a role in slowing down the aging process and enhancing longevity.
Caffeine has been associated with various health benefits, including a decreased risk of age-related illnesses.
Conducted by researchers from Queen Mary University of London, this study explored the inner workings of caffeine within human cells and its relationship to nutrient and stress-responsive gene and protein networks.
The findings revealed that caffeine influences aging by engaging an ancient cellular energy system.
The study demonstrated that caffeine activates a crucial system known as AMPK, which serves as a cellular fuel gauge conserved through evolution in both yeast and humans.
“When energy levels in your cells are low, AMPK activates to assist them,” stated Dr. Charalampos (Babis) Rallis, Reader in Genetics, Genomics, and Fundamental Cell Biology at Queen Mary’s University of London’s Centre for Molecular Cell Biology.
“Our findings reveal that caffeine can help trigger that response,” Rallis added, as detailed in the journal Microbial Cell.
Interestingly, AMPK is also the target of metformin, a widely used diabetes medication currently being researched for its potential to extend human lifespan, along with rapamycin.
Using a yeast model, the researchers illustrated how caffeine's impact on AMPK affects cellular growth, DNA repair, and stress response—all critical factors related to aging and disease.
“These discoveries clarify why caffeine could be advantageous for health and longevity,” noted Dr. John-Patrick Alao, the postdoctoral research scientist leading this study.
“These insights pave the way for exciting future research on how we might more directly induce these effects through diet, lifestyle, or innovative medications,” Alao concluded.