Can Indian Researchers Revolutionize Early Detection of Bone Cancer?

Synopsis
Key Takeaways
- Breakthrough technology for early-stage bone cancer detection.
- Portable and cost-effective device ideal for rural healthcare.
- Utilizes osteopontin (OPN) biomarker for accurate diagnosis.
- Designed as a reagent-less immunosensor for on-the-spot testing.
- Aligns with government initiatives like Make in India.
New Delhi, June 27 (NationPress) In a remarkable advancement in medical technology, scientists from IIT (BHU) in Uttar Pradesh have introduced a compact, self-reporting diagnostic tool capable of accurately identifying early-stage bone cancer.
This innovative sensor detects osteopontin (OPN), a vital biomarker linked to bone cancer.
The device is reagent-free, portable, and economically viable, making it suitable for rural healthcare settings, as stated by the research team led by Dr. Pranjal Chandra from the School of Biochemical Engineering.
Functioning similarly to a glucose meter, the device allows for swift, precise, and on-the-spot diagnosis, even in areas with limited resources.
By utilizing a custom sensor surface made from gold and redox-active nanomaterials, it operates effectively like a glucose meter.
“This innovation simplifies cancer detection and empowers primary health centers,” noted Prof. Chandra. The research findings are published in the esteemed journal Nanoscale (Royal Society of Chemistry, UK).
OPN serves as a crucial biomarker for osteosarcoma, a highly aggressive type of bone cancer that predominantly affects children and teenagers.
While existing methods for detecting OPN are expensive and lengthy, the new device provides quick and accurate results with minimal equipment requirements.
Designed as a reagent-less immunosensor, it facilitates on-the-spot and affordable testing, particularly advantageous in rural and resource-limited regions where early cancer detection is often delayed.
Cancer represents a significant public health challenge in India, with increasing incidence rates and considerable mortality.
Commending the innovation, Director Prof. Amit Patra described it as “a prime example of technology with a human touch.” He emphasized its contribution to precision medicine and national health priorities, aligning with the government’s Make in India and Start-up India initiatives.
A patent application has been submitted, and researchers are working on transforming the prototype into a smartphone-compatible diagnostic kit for enhanced remote healthcare access.