Does RSV Increase the Risk of In-Hospital Cardiac Events More than Flu or Covid in Adults?

Synopsis
Key Takeaways
- RSV poses a higher risk of cardiovascular events compared to flu and Covid-19.
- 11% of hospitalized RSV patients experienced acute cardiac events.
- Individuals with a cardiac history are at increased risk during RSV hospitalization.
- Vaccination may help mitigate risks associated with respiratory viral infections.
- Research emphasizes the need for further studies on RSV and cardiovascular health.
New Delhi, May 23 (NationPress) Individuals suffering from RSV (respiratory syncytial virus) are at a greater risk of experiencing in-hospital cardiac events compared to those with flu or Covid-19, reveals a recent study.
Researchers at the National Centre for Infectious Diseases in Singapore conducted a comprehensive nationwide investigation involving 32,960 adults hospitalized due to RSV, flu, or Covid infections.
The study focused on the comparative risk of cardiovascular events (including any cardiac, cerebrovascular, or thrombotic event) and intensive care unit (ICU) admissions among these patients.
Out of the total 32,960 individuals, 6.5% were diagnosed with RSV, while 43.7% had flu, and 49.8% were infected with Covid.
The findings published in JAMA Network Open indicated that approximately 11% of patients with RSV experienced a cardiovascular event.
“One in ten patients hospitalized for RSV had a concurrent acute cardiovascular event. The odds of cardiac events were significantly elevated in RSV compared to Covid-19 hospitalizations, regardless of vaccination status,” the research team noted.
The research revealed that 1,037 patients (3.2%) required ICU admission. Among the 2,148 RSV patients, 10.9% encountered an acute cardiovascular event, with 94.1% of these being cardiac-related (including 99 cases of abnormal heart rhythm, 66 episodes of heart failure, and 61 instances of ischemic heart disease).
Atrial fibrillation or flutter was the most prevalent abnormal heart rhythm, accounting for 60.6%. Those with a history of cardiac disease exhibited more than double the risk of acute cardiovascular events when compared to flu or Covid-19 patients.
Moreover, a higher likelihood of abnormal heart rhythms, heart failure, and other cardiac complications was observed in RSV patients than in non-boosted Covid patients. However, RSV patients displayed lower odds of cerebrovascular events compared to vaccinated Covid patients.
Individuals with pre-existing cardiac conditions were found to be at an increased risk of acute cardiac events during hospitalization for RSV.
“The cardiac manifestations associated with RSV are believed to stem either from direct myocardial injury or indirectly through a post-inflammatory response coupled with heightened cardiovascular strain due to pulmonary disease,” the researchers explained.
They emphasized the necessity of assessing the role of vaccination in mitigating the risk of cardiovascular events linked to vaccine-preventable respiratory viral infections.