Can even healthy infants be severely impacted by RSV?

Synopsis
Key Takeaways
- RSV poses significant risks to healthy infants, especially under three months.
- 3.6 million hospitalizations occur annually due to RSV in young children.
- Healthy infants can still suffer severe illness from RSV.
- Preventive treatments and vaccines are now available.
- Understanding risk factors is crucial for prevention.
New Delhi, Sep 10 (NationPress) A recent study reveals that even healthy, full-term infants face a noteworthy risk of requiring intensive medical care or extended hospitalization due to severe respiratory syncytial virus (RSV) infections, particularly in the first three months of life.
RSV is a prevalent cause of respiratory infections among young children, leading to around 3.6 million hospitalizations and approximately 100,000 deaths attributed to RSV in children under five each year.
While it is established that premature infants and those with chronic health issues are more susceptible to severe illness from RSV, the prevalence of severe disease in previously healthy children remains less understood.
Researchers at Karolinska Institutet in Sweden examined data from over 2.3 million children born in Sweden between 2001 and 2022 to identify the groups most at risk of serious complications or mortality from RSV.
The results, published in The Lancet Regional Health-Europe, indicated that the majority of children who required intensive care or faced long hospital stays were under three months old, previously healthy, and born at full term.
"It's crucial to consider that even healthy infants can experience severe consequences from RSV when developing treatment protocols," stated Giulia Dallagiacoma, a physician and doctoral student at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet.
In the study, 1.7 percent of the children were diagnosed with RSV infection, with nearly 12 percent (4,621 children) experiencing a severe illness.
The researchers also pinpointed several factors associated with a heightened risk of requiring intensive care or facing mortality.
Children born in winter, those with siblings aged 0-3 years or twins, faced about a threefold increased risk, while those born small had nearly a fourfold increased risk.
Children with underlying medical conditions had over a fourfold increased risk of severe illness or death.
"The positive aspect is that there are now preventive treatments for newborns and vaccines available for pregnant women," Dallagiacoma emphasized.