Are High Levels of Superbugs in Delhi's Environment a Public Health Threat?
Synopsis
Key Takeaways
- High levels of antibiotic-resistant superbugs detected in Delhi.
- Study conducted by researchers at Jawaharlal Nehru University.
- 73% of MRS isolates showed multidrug resistance.
- Airborne contamination poses serious public health risks.
- Urgent need for comprehensive environmental AMR surveillance.
New Delhi, Dec 30 (NationPress) Significant concentrations of antibiotic-resistant superbugs have been detected in both indoor and outdoor environments across Delhi, raising serious public health concerns, as indicated by a recent study.
The presence of airborne microbial contamination, particularly involving antibiotic-resistant bacteria and associated resistance genes, is increasingly alarming in urban settings.
This research, conducted by scientists from Jawaharlal Nehru University, examined the prevalence and diversity of staphylococci, particularly methicillin-resistant staphylococci (MRS), in bioaerosols collected from various urban locations in Delhi, India.
Air samples, both indoors and outdoors, exhibited staphylococcal loads significantly exceeding the WHO's recommended limits for microbial exposure.
Seasonal analysis indicated a surge in airborne MRS during the winter months, while monsoon rains led to a decrease in outdoor bioaerosol contamination.
The researchers assessed staphylococci prevalence in bioaerosols from diverse urban areas in Delhi, including Vasant Vihar Urban Slum (VVUS), Munirka Market Complex (MMC), Munirka Apartment (MA), and the Sewage Treatment Plant at Jawaharlal Nehru University (STP, JNU).
“Eight distinct staphylococcal species were identified, with Staphylococcus epidermidis and Staphylococcus arlettae being the most frequently found species associated with humans and animals, respectively,” stated researchers Himani Kumari and Madhuri Singh from JNU’s School of Environmental Sciences.
Alarmingly, 73% of MRS isolates displayed multidrug resistance (MDR), showcasing resistance to common antibiotics such as macrolides and beta-lactams.
Genotypic analysis revealed the existence of ARGs among airborne MRS, which encode resistance to beta-lactam, trimethoprim, gentamicin, macrolides, chloramphenicol, and lincosamides.
Importantly, 14 out of 36 MDR isolates contained the mecA gene, which is linked to methicillin resistance.
“This study highlights the potential health risks associated with airborne reservoirs of antibiotic resistance in urban contexts and emphasizes the critical need for comprehensive environmental surveillance of AMR to formulate effective mitigation strategies,” the researchers noted.
The findings underscore the urgent requirement for thorough monitoring and reporting on environmental AMR, covering both antibiotic-resistant bacteria and their genetic markers.
“Such initiatives are vital to accurately gauge the extent of the AMR threat and to devise integrated action plans to tackle the escalating challenges posed by AMR in urban landscapes,” the researchers stated.