Could Tongue Scans Be Key to Detecting Motor Neurone Disease?
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New Delhi, Oct 28 (NationPress) Scanning MRI of an individual’s tongue might assist in the early identification and continuous monitoring of Motor Neurone Disease (MND), a neurodegenerative disorder, according to recent research.
Researchers from the University of Queensland in Australia discovered that individuals diagnosed with MND, also known as ALS, who experience challenges with speaking or swallowing often exhibit reduced tongue muscle size.
This finding could act as an initial warning sign of neurodegenerative ailments, stated Dr. Thomas Shaw from the university’s School of Electrical Engineering and Computer Science.
“Our tongues comprise eight interconnected muscles, each serving a unique function, enabling us to eat, swallow, and communicate. However, for those afflicted by motor neuron disease, these tongue muscles—similar to various other muscles in the body—gradually weaken and unfortunately, deteriorate,” Dr. Shaw explained.
“The ability to identify and monitor this symptom early would benefit both patients and healthcare providers, particularly with interventions such as early entry into clinical trials,” he added.
Traditionally, investigating tongue muscles within the mouth of someone living with MND has been challenging and invasive; however, the research team analyzed over 200 historical MRI scans, including some from individuals with MND, for their study.
“By employing a combination of AI-driven and advanced imaging methodologies, we achieved accurate measurements of tongue muscle volume and morphology,” Dr. Shaw noted.
“Comparative cross-sectional analysis revealed significant discrepancies between the scans of those with MND and their healthy counterparts,” he continued.
The study, published in Computers in Biology and Medicine, corroborated earlier findings indicating that individuals whose MND symptoms manifest in the mouth, tongue, throat, and neck muscles tend to have a reduced survival duration compared to those whose symptoms begin in their limbs.
Speech pathologist Dr. Brooke-Mai Whelan from UQ’s School of Health and Rehabilitation Sciences mentioned that the tongue is a complex organ performing thousands of precisely coordinated actions daily, which only become apparent when they start to falter.
“Identifying which specific tongue muscles deteriorate in MND will aid us in formulating strategies to adapt, such as altering a person’s speech patterns to utilize unaffected muscle groups,” she stated.