Could Sugary Drinks Accelerate Colorectal Cancer?
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Synopsis
A groundbreaking study reveals that the glucose-fructose mix in sugary drinks may worsen advanced colorectal cancer. Researchers from the University of Texas MD Anderson Cancer Center found that dietary choices impact cancer risk and progression. This raises questions about current dietary recommendations for cancer patients.
Key Takeaways
- Sugary drinks may worsen colorectal cancer progression.
- Glucose-fructose mix enhances cancer cell mobility.
- SORD activation drives metastasis in colorectal cancer.
- Current dietary guidelines may need revision.
- Statins could be repurposed to help cancer patients.
New Delhi, Sep 20 (NationPress) A recent study conducted by US researchers has revealed that the combination of glucose and fructose present in sugary beverages may significantly contribute to the rise in advanced colorectal cancer cases.
To fulfill their nutritional requirements, numerous cancer patients are advised to consume nutritional supplement drinks and concentrated juices that are high in glucose and fructose.
A team from the University of Texas MD Anderson Cancer Center investigated the impact of sugary drinks on late-stage colorectal cancer.
According to Jihye Yun, Assistant Professor of Genetics at the university, "Our research underscores the importance of daily dietary choices not only in terms of cancer risk but also regarding disease progression once it has manifested."
Utilizing laboratory cancer models, they assessed the effects of the glucose-fructose blend found in many sugary drinks compared to glucose or fructose in isolation.
Only the sugar combination enhanced the mobility of cancer cells, facilitating a quicker spread to the liver, which is the primary site for colorectal cancer metastasis.
This sugar mix activated an enzyme known as sorbitol dehydrogenase (SORD), which increases glucose metabolism and initiates the cholesterol pathway, consequently promoting metastasis.
Interestingly, this pathway is also targeted by statins, widely used heart medications that inhibit cholesterol production.
Inhibiting SORD was found to slow down metastasis, even in the presence of the sugar blend. These findings, published in the Nature Metabolism journal, indicate that focusing on SORD could open avenues for blocking metastasis.
Historically, sugar has been linked to a higher cancer risk, often through obesity.
A previous investigation conducted by Yun's team indicated that even moderate consumption of sugary drinks directly fueled tumor growth in early-stage colorectal cancer, independent of obesity.
Yun emphasized that it might be valuable to reconsider existing dietary guidelines to lessen sugary drink intake among cancer patients.
"While these findings warrant further exploration, they imply that reducing sugary drink consumption, targeting SORD, or repurposing statins could be advantageous for colorectal cancer patients," Yun stated.
Point of View
It's crucial to highlight that this study sheds light on how dietary choices can influence cancer progression. The link between sugary drinks and cancer growth must be taken seriously, and it may be time for healthcare professionals to reevaluate dietary guidelines for cancer patients.
NationPress
20/09/2025
Frequently Asked Questions
How do sugary drinks affect colorectal cancer?
Sugary drinks containing glucose and fructose may enhance cancer cell mobility and promote metastasis to the liver.
What is SORD and its role in cancer?
SORD is an enzyme activated by the sugar mix that accelerates glucose metabolism and triggers pathways leading to metastasis.
Should cancer patients reduce sugary drink intake?
Yes, the study suggests that reducing sugary drink consumption could be beneficial for cancer patients.
Are these findings conclusive?
While promising, further research is necessary to fully understand the implications of these findings.
What dietary changes are recommended for cancer patients?
Consider reducing sugary drink intake and focusing on a balanced diet to support overall health.
